{"id":2223,"date":"2020-07-28T10:00:13","date_gmt":"2020-07-28T10:00:13","guid":{"rendered":"http:\/\/livinglight.icfo.eu\/?page_id=2223"},"modified":"2023-09-14T19:55:00","modified_gmt":"2023-09-14T19:55:00","slug":"project-2","status":"publish","type":"page","link":"https:\/\/livinglight.icfo.eu\/?page_id=2223","title":{"rendered":"Project 1"},"content":{"rendered":"\n<h3 class=\"wp-block-heading has-text-align-center\"> Post-doctoral position in microfluidic cell sorting to understand the mitochondrial basis of ageing<\/h3>\n\n\n\n<p class=\"has-very-light-gray-color has-text-color wp-block-paragraph\">Subject: Postdoctoral scholar position in the lab of Neurophotonics and Mechanical Systems Biology group led by Dr. Michael Krieg (Professor, ICFO) to study impact of age on mitochondrial physiology.<\/p>\n\n\n\n<p class=\"has-very-light-gray-background-color has-background wp-block-paragraph\">The Krieg lab at ICFO is interested in the mechanical control of\nphysiological processes involving the sensation of mechanical stresses. We\nprimarily work with invertebrate model organisms such as Drosophila and C\nelegans and guide our experiments with theoretical models and simulations. We\nuse advanced imaging and biophysical measurements to infer how mechanical\nproperties of molecules, cells and tissues governs neuronal biology.<\/p>\n\n\n\n<p class=\"has-cyan-bluish-gray-color has-text-color wp-block-paragraph\">The successful candidate will be joining the Group of Neurophotonics and Mechanical Systems Biology group led by Michael Krieg in the frame work of an international collaboration between ICFO, LMU Munich and UC Santa Barbara. The main task of the advertised position is to build multilayer optofluidic device for single cell sorting followed by DNA extraction and on chip amplification. The device shall combine optical sorting of cells expressing fluorescent biomarkers for on chip lifespan determination and DNA extraction. The ultimate goal is to decipher the role of replicative lifespan of yeast cells in mitochondrial health and DNA damage. The successful candidate will autonomously fabricate dual layer device for fluid control using Quake valves and feel comfortable to operate in a clean room and test it in a real world scenario to trouble shoot its performance.<br>The Krieg lab has extensive experience in mechanobiology in C. elegans and zebrafish using advanced microscopy techniques, microfluidics and optical tweezers to interrogate fundamental mechanical processes in neurons and during development. The successful candidate will have access to a fully equipped cleanroom, microscopy facility and optical tweezer setup in addition to a stimulating research environment at ICFO.<\/p>\n\n\n\n<p class=\"has-very-light-gray-color has-text-color wp-block-paragraph\"><strong>Eligibility\nand Conditions<\/strong><\/p>\n\n\n\n<p class=\"has-very-light-gray-color has-text-color wp-block-paragraph\">Candidates must hold an\ninternationally-recognized Ph.D.-equivalent degree (or evidence of its completion in the nearest\nfuture) preferably in (bio)-engineering, biosystems design or biophysics. The\nsuccessful candidate should have received formal training in a clean room and\nproven track record of microfluidic design and microscopy, with a strong\npersonal motivation for basic science. Prior work with genetic model organism C. elegans\nand\/or mammalian tissue culture is considered an asset. Proof of ambition, productivity, and\ncreativity is a must, and a track record of conference presentations and first\nauthor peer-reviewed publications will be expected. We are looking for a desire\nto engage in discussions, collaborate with team members and enjoy thinking\ndeeply while developing ideas independently.<\/p>\n\n\n\n<p class=\"has-very-light-gray-color has-text-color wp-block-paragraph\">No restrictions of\ncitizenship apply to the ICFO post-doctoral contracts. The\ncontract is offered for periods of one year, renewable for a total of up to 3\nyears. To ensure candidates are competitive for external fellowship\nopportunities, successful applicants will have completed their terminal degree\nno more than 1 year before the beginning of this appointment.<\/p>\n\n\n\n<p class=\"has-cyan-bluish-gray-color has-text-color wp-block-paragraph\"><strong>Application\nprocedure<\/strong><\/p>\n\n\n\n<p class=\"has-cyan-bluish-gray-color has-text-color wp-block-paragraph\">The formal\napplication should be submitted online via <a href=\"http:\/\/jobs.icfo.eu\">http:\/\/jobs.icfo.eu<\/a>.<\/p>\n\n\n\n<p class=\"has-cyan-bluish-gray-color has-text-color wp-block-paragraph\">Suitable\ncandidates are requested to submit:<\/p>\n\n\n\n<p class=\"has-cyan-bluish-gray-color has-text-color wp-block-paragraph\">&#8211; Presentation\nletter with a declaration of interest, past achievements and future career\ngoals<\/p>\n\n\n\n<p class=\"has-cyan-bluish-gray-color has-text-color wp-block-paragraph\">&#8211; Curriculum Vitae,\nincluding contact details and the contact e-mail of three potential referees.<\/p>\n\n\n\n<p class=\"has-cyan-bluish-gray-color has-text-color wp-block-paragraph\">&#8211; Publication\nlist<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Post-doctoral position in microfluidic cell sorting to understand the mitochondrial basis of ageing Subject: Postdoctoral scholar position in the lab of Neurophotonics and Mechanical Systems Biology group led by Dr. Michael Krieg (Professor, ICFO) to study impact of age on mitochondrial physiology. The Krieg lab at ICFO is interested in the mechanical control of physiological &hellip; <a href=\"https:\/\/livinglight.icfo.eu\/?page_id=2223\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Project 1<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":2134,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"footnotes":""},"class_list":["post-2223","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/livinglight.icfo.eu\/index.php?rest_route=\/wp\/v2\/pages\/2223","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/livinglight.icfo.eu\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/livinglight.icfo.eu\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/livinglight.icfo.eu\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/livinglight.icfo.eu\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2223"}],"version-history":[{"count":3,"href":"https:\/\/livinglight.icfo.eu\/index.php?rest_route=\/wp\/v2\/pages\/2223\/revisions"}],"predecessor-version":[{"id":2519,"href":"https:\/\/livinglight.icfo.eu\/index.php?rest_route=\/wp\/v2\/pages\/2223\/revisions\/2519"}],"up":[{"embeddable":true,"href":"https:\/\/livinglight.icfo.eu\/index.php?rest_route=\/wp\/v2\/pages\/2134"}],"wp:attachment":[{"href":"https:\/\/livinglight.icfo.eu\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2223"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}